ASTRA and its associated studies, CIPHER and AURAH, present independent research funded by the National Institute for Health Research (NIHR) under its Programme Grants for Applied Research funding scheme (RP-PG-0608-10142).

The studies were some of the components of CAPRA, a programme for the Comprehensive Assessment of the Prevention Role of Antiretroviral therapy.

The studies also received support through the Comprehensive Clinical Research Network.

This website is provided courtesy of University College London.

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Papers

Published papers and journal articles based on data from the ASTRA, CIPHER and AURAH studies:

Implications for a policy of initiating antiretroviral therapy in people diagnosed with human immunodeficiency virus: the CAPRA research programme

Miltz A, Phillips A N, Speakman A, Cambiano V, Rodger A & Lampe F C.

Programme Grants for Applied Research Volume: 5, Issue:18, November 2017. DOI: 10.3310/pgfar05180
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Eligibility for PrEP among MSM attending GUM clinics in the UK

Ada Rose Miltz, Valentina Cambiano, Fiona C Lampe, Janey Sewell, Andrew Speakman, Andrew N Phillips, Daniel R Ivens, David Asboe, Simon Collins, Michael Brady, Nneka C Nwokolo, Alison J Rodger, the AURAH Study Group

Sexually Transmitted Infections, December 2017. DOI: 10.1136/sextrans-2017-053268
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Self-Reported Decline in Everyday Function, Cognitive Symptoms, and Cognitive Function in People With HIV

Laverick, Rosanna; Haddow, Lewis; Daskalopoulou, Marina; Lampe, Fiona; Gilson, Richard; Speakman, Andrew; Antinori, Andrea; Bruun, Tina MD; Vassilenko, Anna; Collins, Simon; Rodger, Alison for the Cognitive Impairment in People with HIV in the European Region (CIPHER) Study Group

JAIDS November 1, 2017;76(Issue 3); e74–e83. doi: 10.1097/QAI.0000000000001468

Condomless sex in HIV-diagnosed men who have sex with men in the UK: prevalence, correlates, and implications for HIV transmission

Marina Daskalopoulou, Alison J Rodger, Andrew N Phillips, Lorraine Sherr, Jonathan Elford, Jeffrey McDonnell, Simon Edwards, Nicky Perry, Ed Wilkins, Simon Collins, Anne M Johnson, William J Burman, Andrew Speakman, Fiona C Lampe for the ASTRA Study Group

Sexually Transmitted Infections, 2017;93:590-598. doi: 10.1136/sextrans-2016-053029
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Clinically significant depressive symptoms and sexual behaviour among men who have sex with men

Ada R. Miltz, Alison J. Rodger, Janey Sewell, Andrew Speakman, Andrew N. Phillips, Lorraine Sherr, Richard J. Gilson, David Asboe, Nneka C. Nwokolo, Amanda Clarke, Mark M. Gompels, Sris Allan, Simon Collins, Fiona C. Lampe, for the AURAH Study Group

British Journal of Psychiatry Open May 2017, 3 (3) 127-137; DOI: 10.1192/bjpo.bp.116.003574
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Poly drug use, chemsex drug use, and associations with sexual risk behaviour in HIV-negative men who have sex with men attending sexual health clinics

Janey Sewell, Ada Miltz, Fiona C. Lampe, Valentina Cambiano, Andrew Speakman, Andrew N. Phillips, David Stuart, Richard Gilson, David Asboe, Nneka Nwokolo, Amanda Clarke, Simon Collins, Graham Hart, Jonathan Elford, Alison J. Rodger, for the Attitudes to and Understanding of Risk of Acquisition of HIV (AURAH) Study Group

International Journal of Drug Policy 2017; 43: 33-43. doi: 10.1016/j.drugpo.2017.01.001
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Multicenter European Prevalence Study of Neurocognitive Impairment and Associated Factors in HIV Positive Patients.

Haddow LJ, Laverick R, Daskalopoulou M, McDonnell J, Lampe FC, Gilson R, Speakman A, Antinori A, Balestra P, Bruun T, Gerstoft J, Nielsen L, Vassilenko A, Collins S, Rodger AJ; Cognitive Impairment in People with HIV in the European Region (CIPHER) Study Group.

AIDS Behav. 2017 Jan 31. doi: 10.1007/s10461-017-1683-z
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Accuracy of self-report of HIV viral load among people with HIV on antiretroviral treatment

Sewell, J., Daskalopoulou, M., Nakagawa, F., Lampe, F., Edwards, S., Perry, N., Wilkins, E., O'Connell, R., Jones, M., Collins, S., Speakman, A., Phillips, A., Rodger, A. and the Antiretrovirals, Sexual Transmission Risk and Attitudes (ASTRA) Study Group

HIV Medicine 2016. DOI: 10.1111/hiv.12477
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Socioeconomic status and treatment outcomes for individuals with HIV on antiretroviral treatment in the UK: cross-sectional and longitudinal analyses

Lisa S Burch, Colette J Smith, Jane Anderson, Lorraine Sherr, Alison J Rodger, Rebecca O’Connell, Anna-Maria Geretti, Richard Gilson, Martin Fisher, Jonathan Elford, Martin Jones, Simon Collins, Yusef Azad, Andrew N Phillips, Andrew Speakman, Margaret A Johnson, Fiona C Lampe, for the Antiretrovirals, Sexual Transmission Risk and Attitudes (ASTRA) Study Group

Lancet Public Health 2016. DOI: 10.1016/S2468-2667(16)30002-0
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Non-disclosure of HIV status and associations with psychological factors, ART non-adherence and viral load non-suppression among people living with HIV in the UK

Marina Daskalopoulou, Fiona C. Lampe, Lorraine Sherr, Andrew N. Phillips, Margaret A. Johnson, Richard Gilson, Nicky Perry, Ed Wilkins, Monica Lascar, Simon Collins, Graham Hart, Andrew Speakman, Alison J. Rodger For the ASTRA Study Group

AIDS and Behavior 2016. DOI: 10.1007/s10461-016-1541-4
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Age, time living with diagnosed HIV infection, and self-rated health

McGowan, J., Sherr, L., Rodger, A., Fisher, M., Miners, A., Anderson, J., Johnson, M., Elford, J., Collins, S., Hart, G., Phillips, A., Speakman, A., Lampe, F., the Antiretrovirals, Sexual Transmission Risk and Attitudes (ASTRA) Study Group

HIV Medicine 2016. DOI: 10.1111/hiv.12398
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A Cross-Sectional Study on Attitudes to and Understanding of Risk of Acquisition of HIV: Design, Methods and Participant Characteristics

Sewell J, Speakman A, Phillips AN, Lampe FC, Miltz A, Gilson R, Asboe D, Nwokolo N, Scott C, Day S, Fisher M, Clarke A, Anderson J, O'Connell R, Apea V, Dhairyawan R, Gompels M, Farazmand P, Allan S, Mann S, Dhar J, Tang A, Sadiq ST, Taylor S, Collins S, Sherr L, Hart G, Johnson AM, Miners A, Elford J, Rodger A

JMIR Res Protoc 2016;5(2):e58. DOI:10.2196/resprot.4873
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Sexual behaviour among people with HIV according to self-reported antiretroviral treatment and viral load status

Fiona C. Lampe, The Antiretrovirals, Sexual Transmission Risk and Attitudes (ASTRA) Study Group

AIDS 2016, Vol 30 No 5, p 1745-1749. DOI:10.1097/QAD.0000000000001104
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Prevalence of recreational drug use is indiscriminate across antiretroviral regimens of differing drug–drug interactions among MSM.

Marina Daskalopoulou, Alison J. Rodger, Andrew N. Phillips, Andrew Speakman and Fiona C. Lampe

AIDS 2016, Vol 30 No 5, p 810-812. DOI:10.1097/QAD.0000000000000994
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Health-related quality-of-life of people with HIV in the era of combination antiretroviral treatment: a cross-sectional comparison with the general population.

Alec Miners, Andrew Phillips, Noemi Kreif, Alison Rodger, Andrew Speakman, Martin Fisher, Jane Anderson, Simon Collins, Graham Hart, Lorraine Sherr, Fiona C Lampe, for the ASTRA (Antiretrovirals, Sexual Transmission and Attitudes) Study

Lancet HIV 2014 September 23. doi:10.1016/S2352-3018(14)70018-9
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Recreational drug use, polydrug use, and sexual behaviour in HIV-diagnosed men who have sex with men in the UK: results from the cross-sectional ASTRA study.

Marina Daskalopoulou, Alison Rodger, Andrew N Phillips, Lorraine Sherr, Andrew Speakman, Simon Collins, Jonathan Elford, Margaret A Johnson, Richard Gilson, Martin Fisher, Ed Wilkins, Jane Anderson, Jeffrey McDonnell, Simon Edwards, Nicky Perry, Rebecca O'Connell, Monica Lascar, Martin Jones, Anne M Johnson, Graham Hart, Alec Miners, Anna-Maria Geretti, William J Burman, Fiona C Lampe

Lancet HIV 2014 September 8. doi: 10.1016/S2352-3018(14)70001-3
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Minimal Cognitive Impairment in UK HIV Positive Men Who Have Sex with Men: Effect of Case Definitions, and Comparison with the General Population and HIV Negative Men.

McDonnell J, Haddow L, Daskalopoulou M, Lampe F, Speakman A, Gilson R, Phillips A, Sherr L, Wayal S, Harrison J, Antinori A, Maruff P, Schembri A, Johnson M, Collins S, Rodger A; for the Cognitive Impairment in People with HIV in the European Region (CIPHER) Study Group.

JAIDS 2014 July 2. doi: 10.1097/QAI.0000000000000273
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Attitudes of People in the UK with HIV Who Are Antiretroviral (ART) Naïve to Starting ART at High CD4 Counts for Potential Health Benefit or to Prevent HIV Transmission.

Alison J. Rodger, Andrew Phillips, Andrew Speakman, Richard Gilson, Martin Fisher, Ed Wilkins, Jane Anderson, Margaret Johnson, Rebecca O'Connell, Simon Collins, Jonathan Elford, Lorraine Sherr, Fiona C. Lampe, for the ASTRA (Antiretrovirals, Sexual Transmission Risk and Attitudes) Study Group

PLoS ONE 2014 9(5): e97340. doi: 10.1371/journal.pone.0097340
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The 'Antiretrovirals, Sexual Transmission Risk and Attitudes' (ASTRA) Study. Design, methods and participant characteristics.

Speakman A, Rodger A, Phillips AN, Gilson R, Johnson M, Fisher M, Wilkins E, Anderson J, O’Connell R, Lascar M, Aderogba K, Edwards S, McDonnell J, Perry N, Sherr L, Collins S, Hart G, Johnson AM, Miners A, Elford J, Geretti A, Burman WJ, Lampe F.

PLoS ONE 2013 8(10): e77230. doi:10.1371/journal.pone.0077230
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